照片
姓名:黄荣清
工作单位:军事科学院军事医学研究院辐射医学研究所
职称/职务:研究员
E-mail: hrongqing@163.com
基本情况:
黄荣清,性别:男,汉族,1965年1月生,江西省南昌人,硕士,研究员,硕士研究生导师,主要从事药物质量控制与现代仪器分析、中药复方代谢组学研究。
主持北京市科技计划项目《络石总木脂素片等创新品种研发及安全性评价技术研究-新肿瘤放疗增敏剂BSQ的临床前研究》(Z131100006513012),装备科研项目《基于代谢组学的快速分析检测系统》(JK20191A060417),北京市自然科学基金《金铃子散复方配伍的代谢组学研究》(编号7172161),国家科技重大专项“重大新药创制”项目《新肿瘤放疗增敏剂BSQ的临床前研究》(2013ZX09102016),国家自然科学基金项目《半夏厚朴汤抗抑郁作用机制的代谢组学研究》(编号21375147)等项目,授权发明专利6项。在Ecotoxicology and Environmental Safety 、Journal of Pharmaceutical and Biomedical Analysis 、Journal of Chromatography B、药学学报、分析化学等期刊发表学术论文120余篇。
主持项目:
(1)北京市科技计划项目:《络石总木脂素片等创新品种研发及安全性评价技术研究-新肿瘤放疗增敏剂BSQ的临床前研究》42万, 2013.1-2017.6.主持 Z131100006513012
(2)装备科研项目:《基于代谢组学的快速分析检测系统》200万,2019.12-2023.12.主持 JK20191A060417
(3)国家自然基金:《半夏厚朴汤抗抑郁作用机制的代谢组学研究》40万,2014.1-2015.12.主持 21375147
(4)国家科技重大专项“重大新药创制”项目《新肿瘤放疗增敏剂BSQ的临床前研究》284万,2013.1-2015.12. 主持 2013ZX09102016
(5)北京市自然科学基金《金铃子散复方配伍的代谢组学研究》15万, 2017.1-2019.12 主持7172161
(6)国家科技重大专项“重大新药创制”项目《新肿瘤放疗增敏剂BSQ的研究》150万, 2009.1-2010.12. 主持 2009ZX09103-016
(7)国家科技重大专项“重大新药创制”综合性新药研究开发技术大平台药物分析及质量控制研究技术平台分题《化学创新药质量控制的突破研究》126万,2012.1-2015.12. 主持2012ZX09301003-001-010
代表性成果:
[1] Zhiheng Li, Siyi Wang, Yipu Dong, Xiaoyao Miao, Bingkun Xiao, Jianyun Yang, Jianfeng Zhao, Rongqing Huang*. Amidoxime functionalized chitosan for uranium sequestration in vivo. Ecotoxicology and Environmental Safety, 2022, 239(2022):113636.
[2] Xiaoyao Miao, Bingkun Xiao, Sufang Shui;Jianyun Yang, Rongqing Huang*, Junxing Dong. Metabolomics analysis of serum reveals the effect of Danggui BuxueTang on fatigued mice induced by exhausting physical exercise,Journal of Pharmaceutical and Biomedical Analysis, 2018,151: 301-309.
[3] Sufang Shui, Xiaorong Cai, Rongqing Huang*, Bingkun Xiao, Jianyun Yang. Metabonomic analysis of serum reveals antifatigue effects of Yi Guan Jian on fatigue mice using gas chromatography coupled to mass spectrometry,Biomed Chromatography,2018, 32: e4085
[4] Sufang Shu, Xiaorong Cai;Rongqing Huang*, Bingkun Xiao, Jianyun Yang. The investigation of anti-inflammatory activity of Yi Guanjian decoction by serum metabonomics approach,Journal of Pharmaceutical and Biomedical Analysis, 2017,133:41-48.
[5] Sufang Shui, Shujie Shen;Rongqing Huang*, Bingkun Xiao, Jianyun Yang. Metabonomic analysis of biochemical changes in the plasma and urine of carrageenan-induced rats after treatment with Yi-Guan-Jian decoction, Journal of Chromatography B, 2016,1033: 80-90.
[6] Yan-Ru Liu, Bing-Kun Xiao, Jian-Yun Yang, Chun-Hua Guo, Shu-Jie Shen;Zhi-Shu Tang, Jun-Xing Dong, Rong-Qing Huang*. 1H-NMR and HPLC-MS/ MS-based global/targeted metabolomic evaluation of Hypericum perforatum L. intervention for menopause, Journal of Functional Foods, 2015, 17:722-741.
[7] Liu YR, Huang RQ*, Xiao BK, Yang JY, Dong JX. 1H NMR metabolic profiling analysis offers evaluation of Nilestriol treatment in ovariectomised rats ,Molecular and Cellular Endocrinology, 2014,387(1-2):19-34.
[8] Xu Lijun, Wang Jing, Xiao Bingkun, Yang Jianyun, Liu Yanru, Huang Rongqing*. Preparation and characterization of a novel polymorph of indiplon, Form alpha. Bioorganic & medicinal chemistry letters, 2012,22(2):963-968.
[9] Liu YR, Li WG;Chen LF, Jiang YL, Yang JY, Xiao BK, Huang RQ*, Dong JX. ABTS*+ Scavenging Potency of Selected Flavonols from Hypericum perforatum L. by HPLC-ESI/MS QQQ: Reaction Observation, Adduct Characterization and Scavenging Activity Determination,Food Research International,2014,58:47-58.